Historia natural de la infección asintomática por COVID-19

Major Cause of Myocardial Injury by COVID-19

The most common cause of myocardial necrosis in patient undergoing COVID-19 infection is microthrombi. These microthrombi resulted quite different in composition vs. thrombi obtained from COVID-19 negative patients and thrombi obtained from infected patients with ACS.  Myocardial injury is common in patients hospitalized for COVID-19 and has worse prognosis. Regardless its frequency, the mechanism and<a href="https://solaci.org/en/2021/03/18/major-cause-of-myocardial-injury-by-covid-19/" title="Read more" >...</a>

ISCHEMIA: New Analysis Might Change Study Outcome Interpretation

A new ISCHEMIA analysis has shown its outcomes are highly dependent on MI definition. The original conclusion had shown a significant difference between invasive and conservative strategies using the most sensible definition of MI: troponin elevation.  When looking at events using MI definition as troponin elevation, we will see the conservative treatment reduces primary end<a href="https://solaci.org/en/2021/02/04/ischemia-new-analysis-might-change-study-outcome-interpretation/" title="Read more" >...</a>

Desempeño de los DES actuales ¿hay margen para mejorar?

Current DES Performance: Is There Room for Improvement?

Head-to-head comparison of current drug-eluting stents (DES) showed contradictory results that led us to believe, for years, that we had reached a plateau. This feeling was also fostered by the disappointment caused by Absorb and bioresorbable-polymer stents. However, this recent article featured in JACC Interventions shows a light at the end of the tunnel with<a href="https://solaci.org/en/2021/02/02/current-des-performance-is-there-room-for-improvement/" title="Read more" >...</a>

Novedades en las guías de prevención primaria de la AHA/ACC

Latest News on AHA/ACC Primary Prevention Guidelines

Most cardiovascular diseases and mortality come down to 4 years of unhealthy habits (smoking, poor diet, obesity and sedentarism) and 3 major risk factors (cholesterol, hypertension, and diabetes).  Ideal cardiovascular health, defined as absence or control of these 7 factors, is far less frequent than we might believe. It is estimated that 87% of the<a href="https://solaci.org/en/2021/01/29/latest-news-on-aha-acc-primary-prevention-guidelines/" title="Read more" >...</a>

Más stents suman evidencia al esquema corto y nos acercamos al “efecto de clase”

More Evidence for Short Term DAPT: Approaching “the Class Effect”

Patients at high risk of bleeding undergoing coronary angioplasty with Orsiro stent can be considered for a short dual antiplatelet scheme.  These data come from the SMART-CHOICE study recently published in JAHA, adding the Orsiro stent to the list of devices supporting 3-month DAPT.  This study included 2993 patients undergoing coronary angioplasty randomized to 3<a href="https://solaci.org/en/2021/01/27/more-evidence-for-short-term-dapt-approaching-the-class-effect/" title="Read more" >...</a>

Nuevas guías de valvulopatías con actualizaciones clave en TAVI e insuficiencia mitral

New Valvular Heart Disease Guidelines with Key TAVI and Mitral Regurgitation Updates

Valvular heart disease management guidelines were updated last week by the AHA and the ACC.  The last complete version had been published in 2014; therefore many of its recommendations have become obsolete before the latest evidence.  The studies that made the FDA approve TAVI for low-risk patients are probably the most important incorporations. They also<a href="https://solaci.org/en/2021/01/07/new-valvular-heart-disease-guidelines-with-key-tavi-and-mitral-regurgitation-updates/" title="Read more" >...</a>

Saturated Fats: Dietary Angels or Demons?

In order to reduce cardiovascular events, dietary guidelines recommend restricting saturated fatty acids—without taking into account differences among them—to <10% of the daily caloric intake. It should be noted that there are many different saturated fatty acids, each with its own biological effect. Moreover, said biological effect could be modified by the food matrix and<a href="https://solaci.org/en/2020/12/31/saturated-fats-dietary-angels-or-demons/" title="Read more" >...</a>

SOLACI PERIPHERAL | 5th Clinical Case: Abdominal Aortic Aneurysm with Hostile Neck

New clinical case from SOLACI PERIPHERAL! This time, we present a case featuring an abdominal aortic aneurysm with hostile neck. With this, we wrap up an intense year during which we published 5 clinical cases to deepen and stimulate the exchange between Latin American interventionist colleagues. Tell us what you think about this case using<a href="https://solaci.org/en/2020/12/23/solaci-peripheral-5th-clinical-case-abdominal-aortic-aneurysm-with-hostile-neck/" title="Read more" >...</a>

The Ten Commandments in Adult Congenital Heart Disease

Adult congenital heart disease is a life-long condition that requires appropriate follow-up by experts. Said follow-up is paramount to diagnosing specific and highly variable complications in a timely manner. The recently published European Society of Cardiology guidelines for the management of congenital heart disease calls for a summary of its most important aspects as “ten<a href="https://solaci.org/en/2020/12/15/the-ten-commandments-in-adult-congenital-heart-disease/" title="Read more" >...</a>

AHA 2020 | AFFIRM-AHF: Suplemento de hierro y menos hospitalizaciones por insuficiencia cardíaca

AHA 2020 | Effect of Evolocumab in Complex Coronary Revascularization

Evolocumab, a PCSK9 inhibitor, has shown significant reduction of complex coronary disease requiring revascularization (be it PCI or CABG). Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors induce plaque regression and could eventually reduce the risk of coronary revascularization, especially complex revascularization.  The FOURIER study randomized 27564 patients with stable CAD already on statins to evolocumab<a href="https://solaci.org/en/2020/11/25/aha-2020-effect-of-evolocumab-in-complex-coronary-revascularization/" title="Read more" >...</a>

cardiac failure