Coronary angioplasty in patients with kidney failure is associated with an increased occurrence of events. This study compared the efficacy of preventing clinical restenosis using an everolimus-eluting stent versus a conventional stent, both implanted in the same patient with lesions in more than one vessel and suffering from kidney failure. The primary endpoint was target...
CHILL-MI: Hypothermia fails to show benefit in patients with acute ST- elevation IAM.
Hypothermia improves myocardial ischemia in animals but studies in humans failed to demonstrate benefit to that extent.We admitted 120 patients experiencing anterior-posterior STEMI with up to 6 hours after onset, randomized to conventional invasive therapy versus conventional invasive therapy associated with hypothermia. The primary endpoint was infarct size by MRI at 4 days.There was no...
PRAMI: Treating other lesions in addition to the culprit of an acute infarction reduces events.
In the context of an ST-segment elevation myocardial infarction, primary angioplasty to treat the culprit lesion improves the prognosis. The role of angioplasty in unrelated arteries is not well established. Between 2008 and 2013, 465 patients with myocardial infarction underwent primary angioplasty and were randomized to preventive (234 patients) vs non-preventive angioplasty (231 patients). The...
PRAGUE 14: Anti-thrombotic therapy before non-cardiac surgery may be associated with a higher incidence of bleeding.
The majority of coronary patients are under anti-thrombotic therapy and its interruption may increase cardiovascular risk, while on the other hand, continuation during a surgical procedure may increase the risk of bleeding. This study, which included 1211 patients who underwent non-cardiac surgery, compared the interruption of anti-thrombotic therapy at least 7 days prior vs continuing...
Allen’s test may not be necessary to select patients eligible for radial access
Original title: Trans-Radial Coronary Catheterization and Intervention Across the Whole Spectrum of Allen’s test Results. Reference: Marco Valgimigli et al. J Am Coll Cardiol. 2014. Epub ahead of print. Radial access is associated with a chance of occlusion of the vessel in between 0.8 % and 30 % according to different series. Given this fact, the Allen...
The first portable and intelligent heart monitor has been developed
The device, which should reach the market this year with the name Nexcor, was developed by a group of specialists in Brazil is the first smart portable heart monitor in the world, which allows remote sending electrocardiograms, ocation of the patient for assistance and early detection heart problems. This device automatically detects earliest variations of...
Clinical presentation of restenosis in the three generations of DES
Original title: Clinical Presentation and Outcomes of Coronary In-Stent Restenosis Across 3-Stent Generations. Reference: Marco A. Magalhaes et al. Circ Cardiovasc Interv. 2014;7:00-00. Studies evaluating the clinical presentation of restenosis after implantation of bare metal stent showed that the recurrence of stenosis is not a benign complication as previously thought, with a significant number of patients with restenosis...
FFR to guide treatment of secondary vessel on bifurcations
Original title: Randomized Comparison of FFR-Guided and Angiography-Guided Provisional Stenting of True Coronary Bifurcation Lesions The DKCRUSH-VI (Double Kissing Crush Versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions VI) Trial. Reference: Shao-Liang Chen et al. J Am Coll Cardiol Intv. 2015. Online before print. Angiography for guiding the need to implant a stent in the side...
Shall we change our daily practice to introduce complete revascularization during AMI? Another study contributes for preventive PCI in AMI.
Original title: Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease: The CvLPRIT Trial. Reference: Gershlick AH et al. J Am Coll Cardiol. 2015 Mar 17;65(10):963-72. Recent studies such as the PRAMI and the one we summarize here show complete revascularization of AMI patients before discharge...
CTO revascularization is beneficial
Título original: Long-Term Survival Benefit of Revascularization Compared UIT Medical Therapy in Practice UIT Coronary Chronic Total Occlusion and Well-Developed Collateral Circulation. Reference: Woo Jin Jan, el at. J Am Coll Cardiol Interv 2015;8:271-9 Multiple studies have shown the benefit of chronic total occlusion (CTO) revascularization, but for patients presenting Rentrop 3 grade collateral circulation (CC), such benefit...