There is significant variation in survival rates after in-hospital cardiac arrest care. It is not clear whether better care is associated to better outcomes. Hospital performance was assessed using six recommendations standardized for American hospitals participating in the program “Get with the Guidelines-Resuscitation”. The analysis included 149551 patients presenting in-hospital cardiac arrest in 447 centers...
Mechanical compression devices could solve manual resuscitation shortcomings and help maintain its quality. This study compared the mechanical chest compression device LUCAS-2 with manual compressions in out of hospital non traumatic cardiopulmonary resuscitation. The study randomized 4471 patients (1652 to LUCAS-2 and 2819 to the control group) primary end point was 30 day survival and...
This paper compares the circumferential ablation technique to isolate pulmonary veins, the ablation technique with a hybrid (linear) technique and the isolation technique of the pulmonary veins in fractionally approach. After 18 month follow-up, atrial fibrillation autonomy was similar among the three groups. Atul Verma2014-09-01 Original title: Optimal method and outcomes of catheter ablation of persistent...
This record has been created in order to evaluate the results of percutaneous aortic valve replacement in the UK and currently includes more than 4500 patients with 100% follow-up for mortality. The 3-year mortality was 61.6 % beyond the device or path. Atrial fibrillation, renal failure, chronic obstructive pulmonary disease and a EuroSCORE > 18.5...
TVT STS / ACC registrywas developed to obtain data from all patients undergoing percutaneous aortic valve replacement (TAVR) in the United States. The clinical outcome at 30 days was recently published (Macket al, JAMA 2013) but there are few data on the longer-term treatment that is already incorporated in clinical practice in the United States.The...
Cardiac surgery with cardiopulmonary bypass results in an inflammatory response of the body that is usually associated with adverse outcome. The preventive use of corticosteroids attenuates this response although the benefit is not documented.7507 patients with a planned cardiac surgery were randomizedto methylprednisolone or placebo with the primary objective of assessing the mortality at 30...
The ducts of the right ventricle to the pulmonary artery are used in approximately 20 % of all patients with congenital defects including tetralogy of Fallot with pulmonary atresia, truncus arteriosus, transposition of great arteries with VSD, pulmonary stenosis, etc.The Melody trans catheter pulmonary valve is composed of three leaflets of bovine jugular vein mounted...
High levels of HDL are known to exert a protective effect. In previous studies, dalcetrapib administration increased HDL 30% from baseline. The objective was to test dalcetrapib in the context of acute coronary syndrome (ACS). 15,871 ACS patients were randomized to receive dalcetrapib or placebo. Primary end point was cardiac death, myocardial infarction, ictus, new...
Phosphodieserase-5 enzyme is activated in heart failure and can limit the beneficial effects of nitric oxide, (NO), in the vasculature, kidney and myocardium. The benefits of phosphodiesterase inhibitors are well documented in erectile dysfunction and pulmonary arterial hypertension. Although some studies with sildenafil in heart failure show reduced ejection fraction, their role in heart failure...
Coronary artery bypass grafting (CABG) without a cardiopulmonary bypass, (CBP), has increasingly become an alternative to the conventional standard (with pump). However, it is still controversial whether there is a decrease in morbidity and mortality between these two techniques. The aim of this study was to compare these two techniques in a high risk population. ...