restenosis

Sub intimal recanalization of superficial femoral , femoropopliteal bypass similar results

Original title: Subintimal Recanalization Plus Stenting or Bypass for Management of Claudicants with Femoro-popliteal Occlusions. Reference: Boufi et al. Eur J Vasc Endovasc Surg. Volume 46 Issue 3 September/2013. The main criticism of sub intimal technique is its relative low permeability compared to the surgical technique . Different studies reported a permeability between 56 and 70 % annually ....

2nd generation drug-eluting stents intended for left main coronary artery

Original title: Zotarolimus- versus Everolimus-Eluting Stents for Unprotected Left Main Coronary Artery Disease. ISAR-LEFT MAIN 2 Study. Reference: Julinda Mehilli et al. J Am Coll Cardiol, article in press. Improvements in 2nd generation drug-eluting stents led to increased efficiency and safety , however there is little information on these new platforms to treat left main coronary artery ....

Pharmacological stent intimal coverage with overlap versus no overlap

Original title: Tissue coverage and neointimal hyperplasia in overlap versus nonoverlap segments of drug-eluting stents 9 to 13 months after implantation: In vivo assessment with optical coherence tomography. Reference: Juan Luis Gutiérrez-Chico et al. Am Heart J 2013;166:83-94.e3. The drug-eluting stent’s (DES) overlapping effect over neointimal healing is not completely understood. Drug overdose, large amounts of polymer and...

Angioplasty to common femoral artery begins to emerge as an alternative to surgery

Original title: Acute and Medium-Term Outcomes of Endovascular Therapy of Obstructive Disease of Diverse Etiology of the Common Femoral Artery. Reference: Philip B. Dattilo et al. Catheterization and Cardiovascular Interventions 81:1013–1022 (2013). Surgical endarterectomy is established as the gold standard for treating injuries to common femoral artery since angioplasty presents some difficulties due to the risk of compromising...

Double DES in bifurcations, double thrombosis risk

Original title: Late Thrombosis After Double Versus Single Drug-Eluting Stent in the Treatment of Coronary Bifurcations A Meta-analysis of Randomized and Observational Studies. Reference: Marco Zimarino et al. J Am Coll Cardiol Intv 2013. Article in press. In the era of drug-eluting stents, (DES), several randomized and observational studies have been conducted trying to find the best strategy...

Safety and superior effectiveness over two years in femoropopliteal region with drug-eluting stents

Original title: Sustained safety and effectiveness of paclitaxel-eluting stents for femoropopliteal lesions: two-year follow-up from the Zilver PTX randomized and single-arm clinical studies. Reference: Michael D. Dake et al. J Am Coll Cardiol 2013. Article in press. Studies with long-term monitoring showed mainly the limited permeability of balloon angioplasty, especially over challenging injuries such as total occlusions or...

Paclitaxel eluting balloon in the femoropopliteal region

Original title: Paclitaxel-Coated Versus Uncoated Balloon Angioplasty Reduces Target Lesion Revascularization in Patients With Femoropopliteal Arterial Disease. A Meta-Analysis of Randomized Trials. Reference: Salvatore Cassese et al. Circ Cardiovasc Interv. 2012;5:582-589. Balloon angioplasty is one of the most frequent alternatives used in patients with peripheral vascular disease, especially in the femoropopliteal region.  However, its effectiveness is reduced in...

It takes more patience to implant stents.

Original title: Duration of Balloon Inflation for Optimal Stent Deployment: Five Seconds Is Not Enough. Reference: Thomas Hovasse et al. Catheterization and Cardiovascular Interventions 81:446–453 (2013). Adequate stent expansion and apposition to the vessel wall is essential to optimize the results of percutaneous transluminal coronary angioplasty (PTCA). If the above is not adequate, it increases the risk of...

Rotational atherectomy is only an interim strategy.

Original title: High-Speed Rotational Atherectomy Before Paclitaxel-Eluting Stent Implantation in Complex Calcified Coronary Lesions. The Randomized ROTAXUS (Rotational Atherectomy Prior to Taxus Stent Treatment for Complex Native Coronary Artery Disease) Trial. Reference: Mohamed Abdel-Wahab et al. J Am Coll Cardiol Intv 2013; article in press Heavily calcified lesions are difficult and may prevent the appropriate expansion of a...

Self-expanding stents improve positioning in primary angioplasty

Original title: Self-Expanding Versus Balloon-Expandable Stents in Acute Myocardial Infarction: Results From the APPOSITION II Study Reference: Robert-Jan van Geuns et al. J Am Coll Cardiol Intv 2012;5:1209–19 Acute myocardial infarction is associated with vasoconstriction and thrombus occlusion. Resolution of these two points during the first hours after primary angioplasty can lead to poor extension and poor positioning...

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