acute myocardial infarction

MitraClip® in real life

Original title:&nbsp;Acute outcomes after MitraClip&reg; therapy in highly aged patients: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) Registry.&nbsp;Reference:&nbsp;Wolfgang Schillinger et al. EuroIntervention 2013; 8-online publish-ahead-of-print April 2013. Recently, percutaneous repair of the mitral valve with MitraClip&reg;, (Abbott Vascular, Santa Clara, CA, USA), has emerged as an option for patients with severe mitral regurgitation,<a href="https://solaci.org/en/2013/04/17/mitraclip-in-real-life/" title="Read more" >...</a>

5 Year Follow Up Outcome of Zotarolimus Eluting Stent

Original title:&nbsp;The &#8220;Final&#8221; 5-Year Follow-Up From the ENDEAVOR IV Trial Comparing a Zotarolimus-Eluting Stent With a Paclitaxel-Eluting Stent. ENDEAVOR IV Investigators&nbsp;Reference:&nbsp;Ajay J. Kirtane et al. J Am Coll Cardiol Intv 2013. Article in press. The ENDEAVOR IV was a randomized controlled study with a noninferiority design that compared the Endeavor zotarolimus eluting stent (Medtronic, Santa<a href="https://solaci.org/en/2013/04/12/5-year-follow-up-outcome-of-zotarolimus-eluting-stent/" title="Read more" >...</a>

Complete revascularization in one procedure is more cost effective and as safe as in stages.

Original title:&nbsp;Staged Versus One-time Complete Revascularization With Percutaneous Coronary Intervention for Multivessel Coronary Artery Disease Patients Without ST-Elevation Myocardial Infarction.&nbsp;Reference:&nbsp;Edward L. Hannan et al. Circ Cardiovasc Interv 2013;6;12-20. There is evidence that in patients with multi-vessel disease affected by an acute coronary syndrome (ACS) with ST segment elevation, only the cause lesion should be treated<a href="https://solaci.org/en/2013/03/04/complete-revascularization-in-one-procedure-is-more-cost-effective-and-as-safe-as-in-stages/" title="Read more" >...</a>

Ischemic preconditioning reduces infarct size in patients treated with primary angioplasty

Original title:&nbsp;Preinfarction Angina Reduces Infarct Size in ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention&nbsp;Reference:&nbsp;Ronald Reiter et al. Circ Cardiovasc Interv. 2013;6:00-00. Ischemic preconditioning (IPC) is a phenomenon whereby transitory ischemia episodes protect the myocardium against a more prolonged episode.&nbsp; Until now, IPC has been the most effective approach to protect the myocardium. Pre infarction<a href="https://solaci.org/en/2013/02/08/ischemic-preconditioning-reduces-infarct-size-in-patients-treated-with-primary-angioplasty/" title="Read more" >...</a>

Spontaneous coronary artery dissection (SCAD) is associated with fibro-muscular dysplasia in other territories

Original title:&nbsp;Spontaneous Coronary Artery Dissection. Prevalence of Predisposing Conditions Including Fibromuscular Dysplasia in a Tertiary Center Cohort&nbsp;Reference:&nbsp;Jacqueline Saw, et al. J Am Coll Cardiol Intv 2013;6:44 &ndash;52 Non atherosclerotic spontaneous coronary artery dissection (Non atherosclerotic SCAD) is a rare disease that is associated with acute myocardial infarction and sudden death.&nbsp; This condition is more common<a href="https://solaci.org/en/2013/01/24/spontaneous-coronary-artery-dissection-scad-is-associated-with-fibro-muscular-dysplasia-in-other-territories/" title="Read more" >...</a>

Intracoronary enalaprilat reduces periprocedural injury.

Original title:&nbsp;Intracoronary Enalaprilat to Reduce Microvascular Damage During Percutaneous Coronary Intervention (ProMicro) Study.&nbsp;Reference:&nbsp;Fabio Mangiacapra et al. J Am Coll Cardiol 2013. Article in press Angiotensin converting enzyme (ACE) inhibitors improve clinical outcomes in patients with coronary artery disease and improve epicardial flow in patients with acute ST-segment elevation.&nbsp; Beyond the long-term protective effect of oral<a href="https://solaci.org/en/2013/01/22/intracoronary-enalaprilat-reduces-periprocedural-injury/" title="Read more" >...</a>

Thrombus Aspiration is useful in AMI

Original title:&nbsp;A Prospective Randomized Trial of Trombectomy Versus No Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesion. MUSTELA (MUltidevice Thrombectomy in Acute ST-Segment ELevation Acute Myocardial Infarction) Trial&nbsp;Reference:&nbsp;Marco De Carlo, et al. J Am Coll Cardiol Intv 2012;5:1223&ndash;30 The main objective during primary PCI is myocardial reperfusion, which is limited by distal<a href="https://solaci.org/en/2013/01/10/thrombus-aspiration-is-useful-in-ami/" title="Read more" >...</a>

Serum fibrinogen is a better predictor of periprocedural events than platelet reactivity.

Original title:&nbsp;Elevated Plasma Fibrinogen Rather Than Residual Platelet Reactivity After Clopidogrel Pre-Treatment Is Associated With an Increased Ischemic Risk During Elective Percutaneous Coronary Intervention.&nbsp;Reference:&nbsp;Lawrence Ang et al. J Am Coll Cardiol 2013;61:23&ndash;34. Platelet function tests have identified differences in the response of each patient to clopidogrel and minor platelet inhibition has been associated with thrombotic<a href="https://solaci.org/en/2013/01/09/serum-fibrinogen-is-a-better-predictor-of-periprocedural-events-than-platelet-reactivity/" title="Read more" >...</a>

Ticagrelor, even better than we thought

Original title:&nbsp;Reduction in First and Recurrent Cardiovascular Events with Ticagrelor Compared with Clopidogrel in the PLATO Study.&nbsp;Reference:&nbsp;Payal Kohli et al. CIRCULATION AHA.112.124248. In analyzing randomized and monitored study outcomes, we usually observe that after the occurrence of any primary outcome event patients are typically blocked for further analysis.&nbsp; This practice limits the information on subsequent<a href="https://solaci.org/en/2013/01/08/ticagrelor-even-better-than-we-thought/" title="Read more" >...</a>

Are reversal flow cerebral protection devices useful in carotid angioplasty?

Original title:&nbsp;Prospective, Multicenter European Study of the GORE Flor Reversal System for Providing Neuroprotection During Carotid Artery Stenting&nbsp;Reference:&nbsp;Dimitrios Nikas, et, al.Catheterization and Cardiovascular Intervention 80:1060-1068&nbsp; Cerebral protection systems (CPS) have proved useful in carotid angioplasty stenting (CAS), although it is not clear what the advantages are in respect to carotid endarterectomy, except in high risk<a href="https://solaci.org/en/2012/12/12/are-reversal-flow-cerebral-protection-devices-useful-in-carotid-angioplasty/" title="Read more" >...</a>

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