coronary disease

Renal angioplasty versus medical treatment, no clinical benefit and only a modest help to control blood pressure

Original title: Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis. CORAL trial. Reference: Christopher J. Cooper et al. DOI: 10.1056/NEJMoa1310753   Between 1 and 5% of the hypertensive population has renal artery stenosis and in general, this is combined with peripheral and coronary vascular disease. The renal artery stenosis may result in hypertension, ischemic nephropathy, and multiple long-term...

Clopidogrel suspension, without rebound in stable patients

Original title: A randomised controlled trial of platelet activity before and after cessation of clopidogrel therapy in patients with stable cardiovascular disease. Reference: Ford I et al. J Am Coll Cardiol. 2013;E-pub ahead of print. Some previous studies have suggested an excess of cardiovascular events after discontinuation of clopidogrel, and this could be due to a rebound...

Clinical factors to help decide between angioplasty and carotid endarterectomy

Original title: A clinical rule (sex, contralateral occlusion, age, and restenosis) to select patients for stenting versus carotid endarterectomy: Systematic review of observational studies with validation in randomized trials. Reference: Touzé E et al. Stroke. 2013;Epub ahead of print Compared with carotid endarterectomy, angioplasty with stent is associated with an increased risk of pre- procedural stroke especially for...

Culprit artery only versus revascularization with ST segment elevation myocardial infarction. The discussion continues

Original title: Complete Versus Culprit-Only Revascularization for Patients with Multi-Vessel Disease Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Systematic Review and Meta-analysis. Reference: Kevin R et al. American Heart Journal, article in press. Primary angioplasty is the preferred reperfusion strategy in patients experiencing a STEMI as it has proven superior to fibrinolysis in reducing...

Noncardiac surgery is safe after 6 months after implantation of a DES

Original title: Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. Reference: Hawn MT et al. JAMA 2013;DOI:10.1001 In the patients who underwent non cardiac surgery and had coronary angioplasty with stent history  within 2 years there was not increased in major cardiac events (MACE ) with the exception of those who were...

Everolimus Eluting Stent in multiple vessels with short SYNTAX score

Original title: A Clinical and Angiographic Study of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With Multivessel Coronary Artery Disease. The EXECUTIVE (EXecutive RCT: Evaluating XIENCE V in a Multi Vessel Disease) Trial. Reference: Flavio Ribichini et al. J Am Coll Cardiol Intv 2013. Article in press. Drug-eluting stents (DES ) have emerged...

Stent Thrombosis in the Real World 

Original title: Incidence and predictors of stent trombosis: a single-centre study of 5833 consecutive patients undergoing coronary artery stenting Reference: Javaid Iqbal et al. EuroInterventional 2013;9:62-69 Though potentially fatal, stent thrombosis is a low frequency event associated to stent malapposition, fractures, resistance to antiplatelet therapies, and diseases such as diabetes and kidney disease, among other factors. 5883 pacients...

Aortic Valvuloplasty in the transcatheter aortic valve implantation era 

Original title: Emerging indications, in-hospital and long-term outcome of balloon aortic valvuloplasty in the transcatheter aortic valve implantation era. Reference: Francesco Saia et al. EuroIntervention 2013;8:1388-1397 Until a few years ago, aortic valvuloplasty had been abandoned by many centers due to its limited results and frequent complications. The current guidelines recommend aortic valvuloplasty to treat patients with symptomatic...

Hybrid revascularization, combining strengths in high-risk patients

Original title: One-Stop Hybrid Coronary Revascularization versus Coronary Artery Bypass Graft and Percutaneous Coronary Intervention for the Treatment of Multivessel Coronary Artery Disease: Three-Year Follow-up Results from A Single Institution. Reference: Liuzhong Shen et al. J Am Coll Cardiol Intv 2013. Article in press. Accepted Manuscript. A mammary bridge to anterior descending artery (LMCA) with a permeability >...

Incomplete revascularization: no longer a binary variable

Original title: Residual SYNTAX score after PCI for triple vessel coronary artery disease: quantifying the adverse effect of incomplete revascularisation. Reference: Christopher J. Malkin et al. EuroIntervention 2013;8:1286-1295. In the angioplasty branch of the SYNTAX study, complete revascularization was reached in 56.7% of the population. On the other hand, in the real world, around 40% of patients that...

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