ticagrelor

ARTE: ¿AsEl fin de la aspirina para los pacientes anticoagulados que reciben angioplastiapirina o aspirina más clopidogrel post TAVI?

The End of Aspirin for Anticoagulated Patients Undergoing PCI

The discussion about the best anti-thrombotic strategy for patients with&nbsp;atrial fibrillation&nbsp;undergoing PCI seemed never-ending until the RE-DUAL PCI trial was published in the New England Journal of Medicine (NEJM). This study has arrived to simplify the tough choice between the risk of a thrombotic event vs. the risk of bleeding with a simpler scheme, without<a href="https://solaci.org/en/2017/11/08/the-end-of-aspirin-for-anticoagulated-patients-undergoing-pci/" title="Read more" >...</a>

Fentanilo en la angioplatia: ¿Cuál es el precio de un mayor confort en el procedimiento?

Fentanyl in Angioplasty: What Is the Price of More Comfort During the Procedure?

Fentanyl is a potent opiate commonly administered in the cath lab. Recently, questions on its safety have been raised by research demonstrating that intravenous morphine significantly delays the absorption of oral P2Y12 platelet inhibitors. The mechanism might be slowed gastric emptying. The Platelet Aggregation with tiCagrelor Inhibition and FentanYl (PACIFY) trial enrolled 212&nbsp;patients undergoing indicated<a href="https://solaci.org/en/2017/10/31/fentanyl-in-angioplasty-what-is-the-price-of-more-comfort-during-the-procedure/" title="Read more" >...</a>

RE-DUAL PCI: Anti-Thrombotic Management in Patients with Atrial Fibrillation and PCI

RE-DUAL PCI outcomes have been published by the &nbsp;New England Journal of Medicine&nbsp;along with their presentation at ESC 2017. The traditional triple anti-thrombotic scheme with dual antiplatelet therapy &nbsp;and&nbsp;warfarin for patients with atrial fibrillation undergoing coronary angioplasty&nbsp;seems to have been left behind. &nbsp; This new study showed that the combination of dabigatran with a P2Y12<a href="https://solaci.org/en/2017/09/04/re-dual-pci-anti-thrombotic-management-in-patients-with-atrial-fibrillation-and-pci/" title="Read more" >...</a>

El uso del ultrasonido intravascular en la angioplastia de tronco no protegido se asocia con mejores resultados en comparación con la angioplastia guiada solo por angiografía.

The use of IVUS in unprotected left main PCI associated to better outcomes, compared to angiography guided PCI

Courtesy of Dr.&nbsp;Gustavo Leiva. Coronary Artery Bypass Graft (CABG) has traditionally been the procedure of choice in patients with left main coronary artery disease. However, the use of percutaneous techniques in this kind of lesions has been on the rise, partly due to recent research showing similar outcomes with both procedures. &nbsp; Unprotected left main<a href="https://solaci.org/en/2017/06/26/the-use-of-ivus-in-unprotected-left-main-pci-associated-to-better-outcomes-compared-to-angiography-guided-pci/" title="Read more" >...</a>

Post DES Dual Antiplatelet Therapy Still under Debate

TOPIC: Benefits of Switching Dual Antiplatelet Therapy in Patients with ACS

Newer P2Y12 blockers are the front-line treatment and dual antiplatelet therapy is indicated for 1&nbsp;year after acute coronary syndrome (ACS). Both prasugrel and ticagrelor offer more ischemic benefit than clopidogrel during the initial phase; however, bleeding complications could increase in the long term. The objective of this study was to assess the safety and efficacy<a href="https://solaci.org/en/2017/05/23/benefits-of-switching-dual-antiplatelet-therapy-in-patients-with-acs/" title="Read more" >...</a>

bifurcaciones tap o culotte provisional stenting

Culotte vs. TAP in Bifurcations: Which is Better?

Courtesy of Dr. Agustín Vecchia. &nbsp; In treating bifurcations, the provisional stenting strategy continues to be preferred. However, a percentage of these lesions must be treated with two stents, which involves different techniques. In provisional stenting, when two stents are required, a recent consensus document of the European Bifurcation Club has recently recommended the TAP<a href="https://solaci.org/en/2016/09/14/culotte-vs-tap-in-bifurcations-which-is-better/" title="Read more" >...</a>

Patients with Plaque Erosion: Management without Stenting

This small study presented at ESC and simultaneously published in the European Heart Journal evaluated patients undergoing acute coronary syndrome caused by plaque erosion identified by optical computed tomography (OCT). The study showed it can be managed with conservative antithrombotic therapy and without stenting. &nbsp; Patients with plaque erosion can receive dual antiplatelet therapy, ticagrelor and aspirin<a href="https://solaci.org/en/2016/09/07/patients-with-plaque-erosion-management-without-stenting/" title="Read more" >...</a>

Six Month DAPT Enough for Nobori BES

Patients treated with A9 biolimus eluting stent with biodegradable polymer (Nobori, Terumo) can receive only six months of dual antiplatelet therapy (DAPT) with no increase in adverse events, compared against more prolonged treatments. &nbsp; The net adverse clinical and cerebrovascular events that included all cause death, MI, cerebrovascular events and major bleeding was: 1.92% for<a href="https://solaci.org/en/2016/09/07/six-month-dapt-enough-for-nobori-bes/" title="Read more" >...</a>

STEMI: Best P2Y12 inhibitor according to network meta-analysis

Original Title: Optimal P2Y12 inhibitor in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a network meta-analysis. Reference: Rafique AM et al. J Am Coll Cardiol Intv 2016;9:1036–46. &nbsp; Courtesy of Dr. Alejandro Lakowsky. &nbsp; &nbsp; Researchers drew up a network meta-analysis incorporating 37 trials with more than 88,000 patients undergoing ST elevation<a href="https://solaci.org/en/2016/06/22/stemi-best-p2y12-inhibitor-according-to-network-meta-analysis/" title="Read more" >...</a>

Morphine Increases Platelet Reactivity in Infarctions

The use of morphine in patients undergoing ST elevation acute coronary syndromes is associated to higher platelet reactivity and lower thrombolysiscapacity, according to this small study. The negative effects seem to resolve 2 days after administration. This transient effect is believed to be the result of the inhibition of the normal muscular activity of the<a href="https://solaci.org/en/2016/04/08/morphine-increases-platelet-reactivity-in-infarctions/" title="Read more" >...</a>

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